A Study on Testosterone-Estradiol Binding Globulin (TeBG)
نویسندگان
چکیده
منابع مشابه
Subunit structure of rabbit testosterone estradiol-binding globulin.
Testosterone estradiol-binding globulin (rbTeBG) of rabbit plasma was purified to homogeneity by the sequential use of ammonium sulfate precipitation, affinity chromatography on 5 alpha-dihydrotestosterone-Sepharose, reactive blue-Sepharose, and finally preparative polyacrylamide gel electrophoresis. An overall purification of greater than 3000-fold was achieved with a recovery of 32%. This pur...
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The aim of this study was to find reasons for the interference of sex-hormone binding globulin (SHBG) in direct radloimmunoassays (RIAs) for testosterone and estradiol. 1251.. labeled testosterone and estradiol were compared with 3Hlabeled testosterone and estradiol for their affinity to SHBG. The 3H-Iabeled steroids bound far more avidly to SHBG than did the corresponding 1251-labeled steroids...
متن کاملSubunit Structure of Rabbit Testosterone Estradiol-binding Globulin*
Testosterone estradiol-binding globulin (rbTeBG) of rabbit plasma was purified to homogeneity by the sequential use of ammonium sulfate precipitation, affinity chromatography on 5a-dihydrotestosterone-Sepharose, reactive blue-Sepharose, and finally preparative polyacrylamide gel electrophoresis. An overall purification of greater than 3000-fold was achieved with a recovery of 32%. This purified...
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Genome-wide association studies (GWAS) have successfully identified common genetic variants that contribute to breast cancer risk. Discovering additional variants has become difficult, as power to detect variants of weaker effect with present sample sizes is limited. An alternative approach is to look for variants associated with quantitative traits that in turn affect disease risk. As exposure...
متن کاملPhysical properties and binding capacity of testosterone-estradiol-binding globulin in human plasma, determined by polyacrylamide gel electrophoresis.
Testosterone-estradiol-binding globulin in human plasma was characterized and quantified by polyacrylamide gel electrophoresis. Testosterone and estradiol were shown to bind to a single homogeneous protein over a wide range of experimental conditions. Testosterone binding to cortisolbinding globulin (transcortin) and estradiol binding to albumin were clearly demonstrated; both transcortin and a...
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ژورنال
عنوان ژورنال: Folia Endocrinologica Japonica
سال: 1981
ISSN: 0029-0661
DOI: 10.1507/endocrine1927.57.11_1609